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Mechanism of Action The mechanism of action of GHK-Cu relies on its ability to extensively modulate gene expression

Many researchers combine both treatments, using minoxidil for immediate blood flow enhancement while GHK-Cu provides regenerative support

Minoxidil's mechanism a systemic vasodilator with no follicle specificity means side effects can extend well beyond the scalp: unwanted facial hair, scalp irritation, contact dermatitis, and (in rare cases) cardiovascular changes from systemic absorption.6 GHK-Cu, as an endogenous peptide acting locally on the cells where it's applied, has no documented systemic side effects and no withdrawal phenomenon when discontinued