fsp1 is a glutathione independent ferroptosis suppressor

fsp1 is a glutathione independent ferroptosis suppressor Unleashing in Human Cancers: Targeting Ferroptosis Protein 1 for Overcoming Therapy Resistance Ferroptosis inhibitors: mechanisms of action

Name: fsp1 is a glutathione independent ferroptosis suppressor Unleashing in Human Cancers: Targeting Ferroptosis Protein 1 for Overcoming Therapy Resistance Ferroptosis inhibitors: mechanisms of action
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Ferroptosis inhibitors: mechanisms of action and therapeutic potential Cellular and Molecular Life Sciences Springer Nature Link FSP1 mediated ferroptosis in cancer: from mechanisms to therapeutic applications Apoptosis Springer Nature Link The dual role of FSP1 in programmed cell death: resisting ferroptosis in the cell membrane and promoting necroptosis in the nucleus of THP 1 cells Molecular Medicine Springer Nature Link PPARa FSP1 axis modulates lipid peroxidation induced neuronal ferroptosis to promote functional recovery in mouse model of traumatic spinal cord injury Cellular and Molecular Life Sciences Springer Nature Link

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Vitamins C and B-complex, along with amino acids, can work synergistically with glutathione to enhance liver detoxification

PE-bound haem was also donated to haem-starved populations during co-culture, suggesting a secondary role for PE as a haem storage site that could be later distributed to nearby starved cells and promote survivability under conditions of fluctuating haem availability (Rodrguez-Arce et al., 2019)