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Inflammopharmacology 30, 11531166

however, aspirin forms a covalent, irreversible inhibition of COX (Fig

Lipid peroxides and their metabolites, such as malondialdehyde (MDA) and 4-hydroxynonenal, damage proteins, membrane integrity, and DNA structure, leading to cell membrane hyperpermeability and ferroptosis (Rochette et al., 2022)