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There is a notable overlap between genes involved in vitiligo and those that have been associated with autoimmune disorders

cobalamin 1 It consists of cobalt as the central atom and a corrin ring that encloses the metal atom

Peer review Peer review information Nature Protocols thanks Makoto Kobayashi, Randall Peterson and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Bulk of the iceberg The bulk of the metabolic iceberg represents impaired mitochondrial biology throughout the body, which lies below the clinical waterline and remains relatively unexplored