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PMID 28843240

Adams, M.D., M.P.H., released a public health advisory to urge more Americans to carry naloxone

However, individual responses to any medication can vary

Endotoxins activate specific membrane receptors termed Toll-like receptors that are members of a class of pro-inflammatory receptors hat recognize pro-inflammatory molecules termed pattern-associated molecular patterns or PAMPS that in turn can activate genes that initiate inflammatory cascades in the host [49, 65]