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The arrested synaptic development in autism has been confirmed in human and animal studies, which found an abundance of thin, disrupted, and immature dendritic spines in different forms of ASD

Together, this makes patients with ALF more susceptible to cerebral edema and subsequent intracranial hypertension

The opt3-3 mutant exhibits reduced Cu in phloem sap and impaired source-to-sink Cu movement, indicating the role of AtOPT3 in Cu phloem loading and redistribution to young tissues and developing seeds (Chia et al., Reference Chia, Yan, Rahmati Ishka, Faulkner, Simons, Huang, Smieska, Woll, Tappero, Kiss, Jiao, Fei, Kochian, Walker, Pieros and Vatamaniuk2023

The stock basket is reconstituted annually to limit tracking error to the S&P 500 Index