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List EO, Sackmann-Sala L, Berryman DE, Funk K, Kelder B, Gosney ES, et al

Journal of Food Processing and Preservation, 46 (10), Article e15633

Notably, the expression of inducible costimulatory molecules (ICOS) on CD4 + T cells is significantly increased in the inflammatory mucosa of IBD patients, and this overexpression promotes the production of inflammatory cytokines such as IL-5 in UC and IFN- in CD, suggesting that ICOS may serve as a potential therapeutic target for IBD [40]