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In excess of mitochondrial acetyl-CoA, PC is activated but PDH is inhibited

If you and your doctor decide to transition from injections to oral therapy, two things are essential for your safety: Strict Daily Adherence : Because passive diffusion relies on a daily supply of B12, missing your pill frequently puts you at a higher risk of relapse compared to receiving a guaranteed intramuscular injection [14]

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Once you dissolve our methyl B12 in saline, youll need to use syringes with needles so that you can inject it