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Tans research shows that (32), curculigo glucoside has a significant anti-arthritis effect, which can significantly inhibit the proliferation of MH7A cells, improve the arthritis symptoms of type II collagen-induced arthritis (CIA) rats and reduce the levels of inflammatory factors (TNF-, IL-1, IL-6, IL-10, IL-12 and IL-17A)

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The first line of defense against superoxide is the presence of a specific member of the family of metalloenzymes called superoxide dismutases (SODs), MnSOD or SOD2, specifically located in the mitochondrial matrix, which catalyzes the dismutation of superoxide anion into H 2 O 2 as shown in Figure 2