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Description

At Month 12, the mean change from baseline in ALP for patients with cirrhosis on seladelpar was -121.4 U/L vs 23.2 U/L for placebo, and -134.8 U/L for seladelpar vs -18.0 U/L for placebo in patients without cirrhosis

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TM6 and TM7 of ghrelin receptor adopt nearly identical conformations to G q -coupled 5-HT 2A receptor and G 11 -coupled M1 receptor (Supplementary Fig