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In a comparative study, repeated exposure of human gingival fibroblasts to CS condensate or to nicotine-rich or nicotine-free e-vapour condensates led to alterations in morphology, suppression of proliferation and induction of apoptosis, with changes in all three parameters greater in cells exposed to CS condensate [29]

In this environment, it is possibly not surprising that those who can are seeking to move the discussion beyond the remit of tobacco

Keep packs sealed when not in use, avoid heat above 75F and humidity above 70%, and don't refrigerate or freeze (cold-shock damages the trichomes)

Studies have found that MMP14 activity and protein was increased in the airway epithelium of tobacco smoke-exposed mice and decreased MMP14 activity and protein could diminish the mucin 5AC, oligomeric mucus/gel-forming (MUC5AC) transcripts that played significant roles in the development of COPD [104]