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Asaba K, Iwasaki Y, Yoshida M, Asai M, Oiso Y, Murohara T, et al

Multiple in vitro studies have demonstrated that NAC actively induces the non-immunological degranulation of mast cells, causing them to dump pre-formed histamine directly into the bloodstream, which can trigger immediate allergic-type symptoms

The understanding of taxonomic relationships evolves as more evidence (chemical or molecular) becomes available and will reflect regional access and disciplinary tradition